Includes bibliographical references and index.

Ch. 1. Global Burden of Cardiovascular Disease / J. Michael Gaziano -- Ch. 2. Heart Disease in Varied Populations / Clyde W. Yancy -- Ch. 3. Economics and Cardiovascular Disease / Mark A. Hlatky and Daniel B. Mark -- Ch. 4. Clinical Decision-Making in Cardiology / Harlan M. Krumholz -- Ch. 5. Measurement and Improvement of Quality of Cardiovascular Care / Thomas H. Lee -- Ch. 6. The Principles of Drug Therapy / Dan M. Roden -- Ch. 7. Principles of Cardiovascular Molecular Biology and Genetics / Elizabeth G. Nabel -- Ch. 8. General Principles of Genetic Factors in Cardiovascular Disease / Reed E. Pyeritz and Christine E. Seidman -- Ch. 9. Genetics of Cardiac Arrhythmias / Silvia G. Priori, Carlo Napolitano and Peter J. Schwartz -- Ch. 10. Genetic Factors in Myocardial Disease / Jonathan G. Seidman, Reed E. Pyeritz and Christine E. Seidman -- Ch. 11. The History and Physical Examination: An Evidence-Based Approach / James C. Fang and Patrick T. O'Gara -- Ch. 12. Electrocardiography / David M. Mirvis and Ary L. Goldberger -- Guidelines: Electrocardiography / Thomas H. Lee -- Ch. 13. Exercise Stress Testing / Bernard R. Chaitman -- Guidelines: Exercise Stress Testing / Thomas H. Lee -- Ch. 14. Echocardiography / Heidi M. Connolly and Jae K. Oh -- Guidelines: Use of Echocardiography / Thomas H. Lee -- Ch. 15. The Chest Radiograph in Cardiovascular Disease / Michael A. Bettmann -- Ch. 16. Nuclear Cardiology / James E. Udelson, Vasken Dilsizian and Robert O. Bonow -- Guidelines: Nuclear Cardiology / Thomas H. Lee and James E. Udelson -- Ch. 17. Cardiovascular Magnetic Resonance / Dudley Pennell -- Guidelines: Appropriateness Guidelines: Cardiovascular Magnetic Resonance / Thomas H. Lee -- Ch. 18. Computed Tomography of the Heart / Stephan Achenbach and Werner G. Daniel -- Guidelines: Appropriateness Guidelines: Cardiac Computed Tomography / Thomas H. Lee -- Ch. 19. Cardiac Catheterization / Charles J. Davidson and Robert O. Bonow -- Ch. 20. Coronary Arteriography and Intravascular Imaging / Jeffrey J. Popma -- Guidelines: Coronary Arteriography / Thomas H. Lee -- Ch. 21. Mechanisms of Cardiac Contraction and Relaxation / Lionel H. Opie -- Ch. 22. Pathophysiology of Heart Failure / Douglas L. Mann -- Ch. 23. Clinical Assessment of Heart Failure / Otto M. Hess and John D. Carroll -- Ch. 24. Diagnosis and Management of Acute Heart Failure / John R. Teerlink -- Ch. 25. Management of Heart Failure Patients with Reduced Ejection Fraction / Douglas L. Mann -- Ch. 26. Heart Failure with Normal Ejection Fraction / Margaret M. Redfield -- Guidelines: Management of Heart Failure / Thomas H. Lee -- Ch. 27. Surgical Management of Heart Failure / Patrick M. McCarthy -- Ch. 28. Assisted Circulation in the Treatment of Heart Failure / Yoshifumi Naka and Eric A. Rose -- Ch. 29. Emerging Therapies and Strategies in the Treatment of Heart Failure / Stefanie Dimmeler, Douglas L. Manu and Andreas M. Zeiher -- Ch. 30. Care of Patients with End-Stage Heart Disease / Linda L. Emanuel and Robert O. Bonow -- Ch. 31. Genesis of Cardiac Arrhythmias: Electrophysiological Considerations / Michael Rubart and Douglas P. Zipes -- Ch. 32. Diagnosis of Cardiac Arrhythmias / John M. Miller and Douglas P. Zipes -- Ch. 33. Therapy for Cardiac Arrhythmias / John M. Miller and Douglas P. Zipes -- Guidelines: Ambulatory Electrocardiographic and Electrophysiological Testing / Thomas H. Lee -- Ch. 34. Cardiac Pacemakers and Cardioverter-Defibrillators / David L. Hayes and Douglas P. Zipes -- Guidelines: Cardiac Pacemakers and Cardioverter-Defibrillators / Thomas H. Lee -- Ch. 35. Specific Arrhythmias: Diagnosis and Treatment / Jeffrey E. Olgin and Douglas P. Zipes -- Guidelines: Atrial Fibrillation / Thomas H. Lee -- Ch. 36. Cardiac Arrest and Sudden Cardiac Death / Robert J. Myerburg and Agustin Castellanos -- Ch. 37. Hypotension and Syncope / Hugh Calkins and Douglas P. Zipes -- Ch. 38. The Vascular Biology of Atherosclerosis / Peter Libby -- Ch. 39. Risk Factors for Atherothrombotic Disease / Paul M. Ridker and Peter Libby -- Ch. 40. Systemic Hypertension: Mechanisms and Diagnosis / Ronald G. Victor and Norman M. Kaplan -- Ch. 41. Systemic Hypertension: Therapy / Norman M. Kaplan -- Guidelines: Treatment of Hypertension / Thomas H. Lee -- Ch. 42. Lipoprotein Disorders and Cardiovascular Disease / Jacques Genest and Peter Libby -- Ch. 43. Diabetes Mellitus, the Metabolic Syndrome, and Atherosclerotic Vascular Disease / Joshua A. Beckman, Peter Libby and Mark A. Creager -- Ch. 44. Nutrition and Cardiovascular Disease / Ronald M. Krauss -- Ch. 45. Primary and Secondary Prevention of Coronary Heart Disease / J. Michael Gaziano, JoAnn E. Manson and Paul M. Ridker -- Ch. 46. Exercise-Based, Comprehensive Cardiac Rehabilitation / Paul D. Thompson -- Ch. 47. Complementary and Alternative Approaches to Management of Patients with Heart Disease / John H. K. Vogel, Rebecca B. Costello and Mitchell W. Krucoff -- Ch. 48. Coronary Blood Flow and Myocardial Ischemia / John M. Canty, Jr. -- Ch. 49. Approach to the Patient with Chest Pain / Christopher P. Cannon and Thomas H. Lee -- Ch. 50. ST-Elevation Myocardial Infarction: Pathology, Pathophysiology, and Clinical Features / Elliott M. Antman and Eugene Braunwald -- Ch. 51. ST-Elevation Myocardial Infarction: Management / Elliott M. Antman -- Ch. 52. Primary Percutaneous Coronary Intervention in the Management of Acute Myocardial Infarction / Gary E. Lane and David R. Holmes, Jr. -- Guidelines: Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction / Thomas H. Lee -- Ch. 53. Unstable Angina and Non-ST Elevation Myocardial Infarction / Christopher P. Cannon and Eugene Braunwald -- Guidelines: Unstable Angina and Non-ST Elevation Myocardial Infarction / Thomas H. Lee -- Ch. 54. Chronic Coronary Artery Disease / David A. Morrow and Bernard J. Gersh -- Guidelines: Chronic Stable Angina / Thomas H. Lee and David A. Morrow -- Ch. 55. Percutaneous Coronary and Valvular Intervention / Jeffrey J. Popma, Donald S. Baim and Frederic S. Resnic -- Guidelines; Percutaneous Coronary and Valvular Intervention / Thomas H. Lee -- Ch. 56. Diseases of the Aorta / Eric M. Isselbacher -- Ch. 57. Peripheral Arterial Diseases / Mark A. Creager and Peter Libby -- Ch. 58. Prevention and Management of Stroke / Larry B. Goldstein -- Ch. 59. Endovascular Treatment of Noncoronary Obstructive Vascular Disease / Andrew C. Eisenhauer and Christopher J. White -- Ch. 60. Diabetes and Heart Disease / Richard W. Nesto -- Ch. 61. Congenital Heart Disease / Gary D. Webb, Jeffrey F. Smallhorn, Judith Therrien and Andrew N. Redington -- Ch. 62. Valvular Heart Disease / Catherine M. Otto and Robert O. Bonow -- Guidelines: Management of Valvular Heart Disease / Thomas H. Lee and Robert O. Bonow -- Ch. 63. Infective Endocarditis / Adolf W. Karchmer -- Guidelines: Infective Endocarditis / Thomas H. Lee -- Ch. 64. The Dilated, Restrictive, and Infiltrative Cardiomyopathies / Joshua M. Hare -- Ch. 65. Hypertrophic Cardiomyopathy / Barry J. Maron -- Ch. 66. Myocarditis / Peter P. Lin and Heinz-Peter Schulthoiss -- Ch. 67. Cardiovascular Abnormalities in HIV-Infected Individuals / Stacy D. Fisher and Steven E. Lipshultz -- Ch. 68. Toxins and the Heart / Richard A. Lange and L. David Hillis -- Ch. 69. Primary Tumors of the Heart / Bruce McManus and Cheng-Han Lee -- Ch. 70. Pericardial Diseases / Martin M. LeWinter -- Ch. 71. Traumatic Heart Disease / Matthew J. Wall, Jr., Danny Chu and Kenneth L. Mattox -- Ch. 72. Pulmonary Embolism / Samuel Z. Goldhaber -- Ch. 73. Pulmonary Hypertension / Stuart Rich and Vallerie V. McLaughlin -- Ch. 74. Sleep Apnea and Cardiovascular Disease / Apoor S. Gami and Virend K. Somers -- Ch. 75. Cardiovascular Disease in the Elderly / Janice B. Schwartz and Douglas P. Zipes -- Ch. 76. Cardiovascular Disease in Women / L. Kristin Newby and Pamela S. Douglas -- Ch. 77. Pregnancy and Heart Disease / Carole A. Watnes -- Guidelines: Pregnancy and Heart Disease / Thomas H. Lee -- Ch. 78. Exercise and Sports Cardiology / Gary J. Balady and Philip A. Ades -- Ch. 79. Medical Management of the Patient Undergoing Cardiac Surgery / Richard J. Gray and Dhun H. Sethna -- Ch. 80. Anesthesia and Noncardiac Surgery in Patients with Heart Disease / Lee A. Fleisher and Kim A. Eagle -- Guidelines: Reducing Cardiac Risk with Noncardiac Surgery / Thomas H. Lee -- Ch. 81. Endocrine Disorders and Cardiovascular Disease / Irwin Klein -- Ch. 82. Hemostasis, Thrombosis, Fibrinolysis, and Cardiovascular Disease / Barbara A. Konkle, Daniel Simon and Andrew I. Schafer -- Ch. 83. Rheumatic Fever / B. Soma Raju and Zohan G. Turi -- Ch. 84. Rheumatic Diseases and the Cardiovascular System / Brian F. Mandell and Gary S. Hoffman -- Ch. 85. The Cancer Patient and Cardiovascular Disease / Thomas Forco -- Ch. 86. Psychiatric and Behavioral Aspects of Cardiovascular Disease / Lawson R. Wulsin and Arthur J. Barsky -- Ch. 87. Neurological Disorders and Cardiovascular Disease / Willam J. Groh and Douglas P. Zipes -- Ch. 88. Interface Between Renal Disease and Cardiovascular Illness / Peter A. McCullough -- Ch. 89. Cardiovascular Manifestations of Autonomic Disorders / Suraj Kapa and Virend K. Somers.

"Dr. Braunwald's masterwork returns ... bringing you the definitive guidance you need to overcome any challenge in clinical cardiology today, using the best approaches available! Hundreds of world authorities, many of them new to this edition, synthesize all of the recent developments that are revolutionizing practice - from the newest findings in molecular biology and genetics to the latest imaging modalities, interventional procedures, and medications. The expertise of the book's contributors, the scope of its coverage, and its richly illustrated, user-friendly format all make this the ultimate reference for the practicing cardiologist."