Overview of defence mechanisms -- Cells and organs of the immune system -- Innate immune responses I -- Innate immune responses II : the complement system -- Innate immune response III : other soluble factors -- Inflammation -- What the immune system recognises -- Human leucocyte antigen (HLA) molecules -- Antigen presentation -- How does the immune system see antigen? -- Lymphocyte maturation -- Immunoglobulin structure -- B cell activation -- Immunoglobulin function -- T cell receptor and immune repertoire -- Helper T cell activation -- Cytotoxic T cells -- The mucosal immune system -- Initiation of the immune response -- Maintenance of the immune response -- Control of the immune response -- Ontogeny of the immune response -- Immune responses to infection -- How organisms evade the immune system -- Consequences of an immune response -- Host defence against tumours -- Autoimmunity -- Hypersensitivity -- Atopy and allergic inflammation -- Clinical manifestations of atopy -- Asthma -- Urticaria and angioedema -- Food allergy -- Anaphylaxis -- Other types of hypersensitivity reactions -- Immunodeficiency -- Defects in antibody-mediated immunity -- Defects in T cell-mediated immunity -- Neutrophil disorders -- Complement deficiency -- Defective splenic function -- Human immunodeficiency virus -- Autoimmunity -- Autoimmune endocrinopathies -- Immune-mediated haematological conditions -- Autoimmune liver diseases -- Immune-mediated gastrointestinal disorders -- Immune-mediated neurological disease -- Immune-mediated skin disease --

Immune-mediated renal disease -- Rheumatoid disease and spondylarthropathies -- Connective tissue diseases -- Vasculitis -- Hypersensitivity induced by pathogens -- Transplantation -- Haemopoietic stem cell transplantation -- Solid organ transplantation -- Lymphoid malignancies -- Leukaemia and lymphoma -- Plasma cell diseases -- Laboratory tests in clinical immunology -- Antibodies are essential tools in the clinical immunology laboratory -- Detection of antibodies and antigen -- Autoantibody profiles in connective tissue diseases and rheumatoid disease -- Autoantibodies associated with vasculitic syndromes and renal diseases -- Autoantibodies associated with liver and gastrointestinal diseases -- Autoantibodies associated with endocrine diseases and pernicious anaemia -- Other organ-specific autoimmunity -- Measurement of the acute phase response -- Complement -- Immunodeficiency -- Abnormal immunoglobulins -- Angioedema : C1-inhibitor diseases -- Allergy and hypersensitivity -- Transplantation -- Immunophenotyping leukaemias and lymphomas -- Direct immunofluorescence -- Principles of immunosuppression -- Corticosteroids -- Immunosuppression (I) -- Immunosuppression (II) -- Therapeutic antibody production -- Targeted cell depletion -- Other antibody therapies -- Immunoglobulin replacement therapy -- High dose immunoglobulin therapy -- Cytokines -- Vaccination and passive immunisation -- Plasmapheresis and plasma exchange -- Management of acute allergic reactions