Includes bibliographical references and index.

Principles of cell and membrane function -- Homeostasis : volume and composition of body fluid compartments -- Signal transduction, membrane receptors, second messengers, and regulation of gene expression -- The nervous system : introduction to cells and systems -- Generation and conduction of action potentials -- Synaptic transmission -- The somatosensory system -- The special senses -- Organization of motor function -- Integrative functions of the nervous system -- The autonomic nervous system and its central control -- Skeletal muscle physiology -- Cardiac muscle -- Smooth muscle -- Overview of circulation -- Elements of cardiac function -- Properties of the vasculature -- Regulation of the heart and vasculature -- Integrated control of the cardiovascular system -- Introduction to the respiratory system -- Static lung and chest wall mechanics -- Dynamic lung and chest wall mechanics -- Ventilation, perfusion, and ventilation/perfusion relationships -- Oxygen and carbon dioxide transport -- Control of respiration -- Nonphysiological functions of the lung : host defense and metabolism -- Functional anatomy and general principles of regulation in the gastrointestinal tract -- The cephalic, oral, and esophageal phases of the integrated response to a meal -- The gastric phase of the integrated response to a meal -- The small intestinal phase of the integrated response to a meal -- The colonic phase of the integrated response to a meal -- Transport and metabolic functions of the liver -- Elements of renal function -- Solute and water transport along the nephron : tubular function -- Control of body fluid osmolality and volume -- Potassium, calcium, and phosphate homeostasis -- Role of the kidneys in the regulation of acid-base balance -- Introduction to the endocrine system -- Hormonal regulation of energy metabolism -- Hormonal regulation of calcium and phosphate metabolism -- The hypothalamus and pituitary gland -- The thyroid gland -- The adrenal gland -- The male and female reproductive systems