"A Lange medical book.."

Previous ed.: 2009

Includes bibliographical references and index

Biochemistry & medicine -- Water & pH -- Amino acids & peptides -- Proteins : determination of primary structure -- Proteins : higher orders of structure -- Proteins : myoglobin & hemoglobin -- Enzymes : mechanism of action -- Enzymes : kinetics -- Enzymes : regulation of activities -- Bioinformatics & computational biology -- Bioenergetics : the role of ATP -- Biologic oxidation -- The respiratory chain & oxidative phosphorylation -- Carbohydrates of physiologic significance -- Lipids of physiologic significance -- Overview of metabolism & the provision of metabolic fuels -- The citric acid cycle : the catabolism of acetyl-CoA -- Glycolysis & the oxidation of pyruvate -- Metabolism of glycogen -- Gluconeogenesis & the control of blood glucose -- The pentose phosphate pathway & other pathways of hexose metabolism -- Oxidation of fatty acids : ketogenesis -- Biosynthesis of fatty acids & eicosanoids -- Metabolism of acylglycerols & sphingolipids -- Lipid transport & storage -- Cholesterol synthesis, transport, & excretion -- Biosynthesis of the nutritionally nonessential amino acids -- Catabolism of proteins & of amino acid nitrogen -- Catabolism of the carbon skeletons of amino acids -- Conversion of amino acids to specialized products -- Porphyrins & bile pigments -- Nucleotides -- Metabolism of purine & pyrimidine nucleotides -- Nucleic acid structure & function -- DNA organization, replication, & repair -- RNA synthesis, processing & modification -- Protein synthesis & the genetic code -- Regulation of gene expression -- Molecular genetics, recombinant DNA, & genomic technology -- Membranes : structure & function -- The diversity of the endocrine system -- Hormone action & signal transduction -- Nutrition, digestion, & absorption -- Micronutrients : vitamins & minerals -- Free radicals and antioxidant nutrients -- Intracellular traffic & sorting of proteins -- Glycoproteins -- The extracellular matrix -- Muscle & the cytoskeleton -- Plasma proteins & immunoglobulins -- Hemostasis & thrombosis -- Red & white blood cells -- Metabolism of xenobiotics -- The biochemistry of aging -- Cancer : an overview -- Clinical biochemistry -- Biochemical case histories

Clear, concise, and in full color, Harper's Illustrated Biochemistry is unrivaled in its ability to clarify the link between biochemistry and the molecular basis of disease. Combining outstanding full-color illustrations with integrated coverage of biochemical diseases and clinical information, Harper's offers an organization and careful balance of detail and brevity not found in any other text on the subject.--COVER