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Molecular cell biology [electronic resource] /

Edition statement:Fifth edition. Published by : W.H. Freeman and Company, (New York : ) Physical details: 977 pages : illustration ISBN: 0716743663; 9780716743668. Year: 2003
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Includes bibliographical references and index.

Chemical and molecular foundations. Life begins with cells ; Chemical foundations ; Protein structure and function ; Basic molecular genetic mechanisms -- Cell organization and biochemistry. Biomembranes and cell architecture ; Integrating cells into tissues ; Transport of ions and small molecules across cell membranes ; Cellular energetics -- Genetics and molecular biology. Molecular genetic techniques and genomics ; Molecular structure of genes and chromosomes ; Transcriptional control of gene expression ; Post-transcriptional gene control and nuclear transport -- Cell signaling. Signaling at the cell surface ; Signaling pathways that control gene activity ; Integration of signals and gene controls -- Membrane trafficking. Moving proteins into membranes and organelles ; Vesicular traffic, secretion, and endocytosis ; Metabolism and movement of lipids -- Cytoskeleton. Microfilaments and intermediate filaments ; Microtubules -- Cell-cycle and cell-growth control. Regulating the eukaryotic cell cycle ; Cell birth, lineage, and death ; cancer

Emphasizing the experimental basis of current understandings in molecular biology, the text introduces experimental methodologies and concepts. Thirteen chapters cover such topics as biomembranes and cell architecture, cell integration in tissues, cell transport mechanisms, cellular energetics, molecular genetic techniques, transcriptional control of gene expression, and signaling at the cell surface

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